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A six-month-old domestic shorthair cat was presented with a history of failure to grow and bilateral corneal opacity caused by corneal oedema.
Congenital hyposomatropism and possible secondary hypothyroidism were diagnosed on the basis of fasting levels of insulin-like growth factor-1 and thyroxine levels. These endocrinopathies are rare in cats and have not been linked previously to ocular signs.
The cat died during the clinical investigation and post mortem examination showed reduced corneal endothelial cell density.
Abstract reproduced by kind permission of Veterinary Practice magazine