Genitrix is encouraging practices to capitalise on the growing market opportunity for dental treatments by offering a free pack of its Dentagen Dental Wax and a special offer of six products for the price of five for the rest of its Dentagen dental range during March 2010.
The company is also urging practices to declare March 'Dental Care Month' and to use it as a platform to step up the education they offer to pet owners on this important welfare issue.
According to Genitrix, the Dentagen range uses a plant extract called RF2 which operates as an 'anti-biofilm' treatment, modifying the membrane of oral bacteria to prevent them from producing plaque even at low concentrations. Dentagen Wax is applied to dogs or cats at the end of dental procedures in practice, while the animal is still sedated. It forms a protective coating over the teeth, which lasts for several days.
Each pack of wax contains five syringes enabling practices to offer free wax applications to pets during Dental Care Month. Pet owners can then maintain the protective coating by giving their pet either Dentagen plaque prevention chews every other day or the Dentagen Aqua drinking water additive.
For dogs, the chews are supplied in two sizes with the larger size designed for dogs over 8 kg and a smaller size for dogs less than 8 kg. Dentagen Aqua is a drinking water additive containing RF2. The company says the palatable liquid, which is added to a pet's drinking water, has proved particularly effective in treating cats which don't respond well to tooth-brushing or dental chews.
Rob Watkins, Genitrix' marketing director said: "It's well known that dental disease affects 80% of pets over three years' old and, if left untreated, can go on to cause serious health problems.
"Data from veterinary practices also confirms that many of them are not achieving the revenue they could from offering dental treatments to their clients. We want them to get their teeth into this important revenue opportunity so we're calling on practices to make March 'Dental Care Month' and are offering them a special deal on Dentagen products to get them started.
"The efficacy of the Dentagen range in inhibiting plaque formation has been proven in clinical trials and it has proved popular with pet owners, increasing their compliance with preventative health regimes."
To order your free pack of Dentagen Wax and to take advantage of the special offer on the rest of the range, contact Genitrix on 01403 786345 or by email at mail@genitrix.co.uk
A DNA test which will save foals from unnecessary pain and suffering, and ultimately death, has been launched by the Animal Health Trust.
Foal Immunodeficiency Syndrome (FIS), a genetic disorder which is known to affect Fell and Dales ponies, causes foals to become anaemic and prone to opportunistic infections. Any foal born with the syndrome will not survive.
The new diagnostic DNA test, which costs £40, is the result of ten years of research by the Animal Health Trust (AHT) and the University of Liverpool. The test will not only identify foals which have the fatal condition but will highlight adult ponies who are carriers of the genetic trait which causes the syndrome. Affected foals will be prevented by avoiding covering a carrier mare with a carrier stallion.
Owners and breeders who wish to find out the genetic status of their ponies can arrange for a simple pulled mane or tail hair sample to be taken by a vet and submitted to the AHT. The Fell Pony or Dales Pony Societies will supply sample bags for submission on request. A fast-track system to identify foals suffering with the condition will report results within three working days.
The team that developed the DNA test was led by the AHT's Dr June Swinburne and Professor Stuart Carter of the University of Liverpool with research student Laura Fox-Clipsham. They believe that by using the test, owners and breeders will eventually be able to eradicate this awful condition.
Dr. June Swinburne, said: "The DNA test gives owners and breeders the power to overcome this devastating illness. It enables them to make informed decisions about which ponies to breed. We have already had samples submitted by HM The Queen from her own breeding stock of Fell ponies. I'd urge any breeders of Fell or Dales ponies to submit samples in order to arm themselves with the facts they need to prevent the birth of affected foals and thereby avoid this distressing condition."
Professor Carter, said: "The research, and ultimately the DNA test, has only been possible thanks to funding from The Horse Trust and the support of the Fell Pony Society and the Dales Pony Society who have supplied DNA samples. We consider that the efforts of all involved in enabling this research have lead to a major advance in animal welfare."
For more information on testing, contact the Fell or Dales Pony Societies. Alternatively visit the AHT website http://www.aht.org.uk/genetics_fis.html or email FIStesting@aht.org.uk
The Pet Doctors Group has announced that it will continue its New Graduate Programme for Autumn 2010, an initiative which the company says has proved successful since its launch in 2008. The aim of the scheme is to appoint new graduates to work in a selected number of its practices, spread across the South East of England.
Brodie Collins, Area Manager at Pet Doctors, will be meeting final year students at the Bristol University School of Veterinary Science, the Royal Veterinary College in London and the University of Cambridge Veterinary School during February and March 2010 to promote the scheme and explain the firm's approach to supporting graduates during their critical first year in practice. Successful applicants will be shortlisted by August 2010 with appointments made by September.
With the economic climate causing many practices to postpone recruitment or reduce support and training for new qualified graduates, competition for places on schemes such as this is expected to be high this year.
Brodie said: "The first twelve months out of vet school can be the most daunting of a vet's career. They're suddenly thrust into a public facing role with little experience of communicating with clients or making a diagnosis. Many have limited surgical experience and even fewer have business acumen. They really need structured support and training to build their confidence and enable them to perform effectively both from a clinical and a business perspective. Mentoring is a key support tool so our graduates are all placed with practices where this can be provided regularly.
Feedback from our scheme last year showed that what the graduates we recruited most valued was working within a team which encouraged them to be open and honest so that they could readily ask for advice and help when they needed it. We're all individuals and perform much better if we feel comfortable with the people we're working with. Our scheme enables us to build on our graduates' strengths and support them in areas which they find more challenging.
We provide clinical and surgical training but also focus on the development of communication and management skills to help graduates fulfil their role as part of a business team. The graduates we appoint will each spend their first year based within one of our smaller practices, working as part of a small and closely knit team. At the end of the first year, if all is going well, they will have the option to stay on and help grow that practice.
In addition to veterinary skills, we're looking for graduates with a good personality fit, a strong work ethic, a caring approach and ideally some level of business understanding."
For further information on the scheme, please contact Brodie at Brodie@petdoctors.co.uk
Intervet / Schering-Plough Animal Health has announced that Optimmune - which is used to treat Keratoconjunctivitis sicca (KCS) in dogs - is back in stock three weeks ahead of schedule following a temporary shortage in January.
Melanie Dass, product manager at Intervet / Schering-Plough Animal Health said: "We were aware that the shortage would happen so took steps to manage the supplies that were available and to resume production as soon as possible.
"We wrote to all our veterinary customers informing them of the likely shortage and fortunately, as a result of doing everything we could to minimise disruption, the product is now back three weeks earlier than expected and we are confident in our long term supply."
Melanie added: "We will be allocating stock in February to ensure all practices receive enough product to meet the needs of clinical cases, which amounts to approximately 125% of average monthly usage. This should allow a smooth return to normal deliveries in March.
"We would like to thank all our veterinary customers for helping us manage the allocation of the product and for their understanding during this difficult situation."
Any practices that require additional stock for clinical cases during February, should contact their Intervet / Schering-Plough account manager or the Veterinary Support Group on 01908 685685.
Intervet/Schering-Plough Animal Health has launched the Intestinal Health Center for Poultry website (www.ihc-poultry.com), a website to keep producers, veterinarians, nutritionists, academics and students informed about this aspect of poultry production.
The company says it has published a wealth of practical, science-driven information and ideas to help producers manage costly gut diseases more effectively through vaccination, nutrition, sanitation and prudent drug use.
Marcelo Lang, global marketing director for the company's Poultry Business Unit said: "The new website lets you find virtually anything you need, quickly and easily, on specific intestinal health topics and products".
The website also offers a library of past issues of the company's Intestinal Health magazine and its predecessor, CocciForum, as well as three newsletters - Broiler Health, Layer Health and Turkey Health. In addition, the website includes an interactive feature called "Gut Reactions," where visitors can answer a frequently updated questionnaire related to intestinal health, immediately view survey results and then access links with more information on that topic. There is also a product finder to help users find Intervet/Schering-Plough Animal Health intestinal health products available in their market.
Marcelo added: "The Intestinal Health Center for Poultry is another example of Intervet/Schering-Plough Animal Health's commitment to educating the industry about this increasingly important segment of poultry health. We look forward to getting feedback on the site so that we can make it even better."
Bayer Animal Health, maker of Advocate, has announced that it will be running its 'Be Lungworm Aware' campaign in April.
The company says the campaign aims to help raise awareness of Angiostrongylus vasorum amongst dog owners and support the veterinary practice as a source of further information. The initiative will be backed by a national TV and print advertising campaign. Media vet Joe Inglis will also be supporting the initiative and will be talking about Angiostrongylus vasorum during a series of radio and web broadcasts.
Bayer has produced new support materials, including an updated lungworm PR pack. The materials are designed to allow veterinary practices to educate owners on the disease, whilst helping to raise the profile of the practice in the local community.
Meanwhile, the research carried out by the company has revealed some interesting insights into dog owners' understanding of lungworm.
Despite awareness being fairly high with nearly half of owners claiming to know about the condition, 84% of this group did not know any of the clinical signs associated with the infection, while only 60% were aware that the disease could be fatal if left untreated. Understanding of how dogs become infected was also relatively low with only 24% of owners recognising the role of slugs and snails as the intermediate host for the parasite. As well as playing a vital role in alerting owners to the emergence of the disease, the veterinary practice was cited as the primary source of information that owners would refer to if they needed advice on treating this parasite.
Eric Morgan from the University of Bristol said: "Angiostrongylus vasorum appears to be continuing its spread to new locations in the UK. It is therefore important that dog owners are educated on the infection and the signs to look out for, to enable them to seek treatment before it is too late."
For further details, or to order the new practice materials, please contact your Bayer representative or ring 0845 2574798 quoting 'Be Lungworm Aware'.
The British Veterinary Association's Council has agreed unanimously to reject Animal Health's proposal to base fees for Official Veterinarians (OVs) on the available budget instead of an hourly rate, which the BVA negotiating team has been pushing for for some time.
The BVA team argued consistently for a professional fee for professional work and based its demands on the independent ADAS report and SPVS fees surveys. Animal Health proposed a matrix for TB testing fees based on the number of animals tested and the distance travelled and said that there would be no further discussion on an appropriate professional fee due to budget constraints. The BVA Council felt strongly that it could not accept a proposal that was based on a finite budget and did not respect the need for a professional fee for veterinary work.
BVA President Bill Reilly said: "While we understand the budget squeeze on Animal Health, BVA Council has taken a principled stand that vets should be paid a professional fee for a professional service, not a fee based on the available budget.
"With the launch of the draft Animal Health Bill last Monday we call on the Government to consider the central role OVs play in this new disease control set up and to provide sufficient funding. Launching the draft Bill, Defra's Minister of State spoke of partnership. OVs are such a partner, professionals integral to the disease prevention and control mechanisms. The country has a major disease problem in TB which requires professionals to ensure control and protection of the public and animals alike.
"Let me clarify that Animal Health will not be negotiating with individual vets - they will simply be paying at the same rate in 2010/11 as in 2009/10 and no guarantee that the budget will not be reduced in the future. Each individual veterinary practice will need to decide whether or not they wish to continue TB testing or other OV work."
The BVA and BCVA are advising members that they will need to take a decision in their own practice on whether or not it is financially viable for them to continue OV work.
Intervet/Schering-Plough Animal Health has announced that it has received marketing authorization from the European Commission for a single-shot vaccination schedule of its Porcilis PCV vaccine against porcine circovirus type 2 (PCV2) infections.
The new approval allows vaccination with 1 dose of 2 ml in pigs from an age of 3 weeks onwards (known as the 1 - 2 - 3 approach) in the case of low to medium levels of maternal antibodies against PCV2, and also to include reduction of mortality as an additional indication. This new single-shot application for Porcilis PCV offers additional flexibility over the currently available dosage scheme of this vaccine, which has been available in Europe since April 2009.
Intervet/Schering Plough says the major characteristics of Porcilis PCV are that: (1) it contains the Cap-2 subunit antigen coded by ORF2 and therefore induces strong immunity against PCV2 infection; (2) it is combined with XSolve, an adjuvant offering immunity until the end of the finishing period; and (3) is able to break through of all levels of maternally-derived antibodies in piglets depending on the vaccination schedule used.
The company adds that one single dose of Porcilis PCV has been demonstrated to induce both humoral and cell-mediated responses against PCV2, despite the presence of low to medium levels of maternal antibodies. According to a recent study published in Vaccine, the immunity induced by a single dose of the vaccine resulted in reductions of viremia, viral shedding and viral load in tissues in vaccinated pigs as compared to controls. Field trials have also demonstrated that vaccination of pigs at 3 weeks of age or older reduces the presence of virus load in the blood and reduces weight loss associated with PCV2 infection during the fattening period.
Infection with PCV2 is known to cause a variety of syndromes in pigs, together known as Porcine Circo Virus Disease (PCVD). Symptoms may include clinical signs such as weight loss or failure to grow, enlarged lymph nodes, difficulty in breathing, pale skin and jaundice.
Practices will be able to offer customers increased support for their worming programmes in 2010, as part of a new initiative from Eqvalan® manufacturer, Merial.
Eqvalan product manager Claire Edmunds said: "The SMART worming campaign is designed to encourage owners to Simply Monitor, Assess Risk and, if necessary, Treat with the most appropriate wormer.
"We know that worming can be confusing for horse owners, so the SMART approach is designed to help them manage their worming programmes more easily, whilst also ensuring that wormers are used in a way that may help prevent the development of resistance.
Practices purchasing Eqvalan Duo during February and March can get 4 tubes free when they purchase 20. In addition, to kick start the SMART campaign for each order on the above offer, Merial will supply 20 free Worm Egg Count vouchers worth £10/€10 each. For those practices with their own testing facilities, the company is also offering promotional support to help encourage increased uptake and client buy-in.
Claire added: "As well as continuing with the successful free worm egg count campaign available for practices during February and March, owners will also have access to a personalised on-line planner, as well as text and email alerts.
"The campaign is being supported with new point of sale material and a prominent consumer advertising campaign. In addition we also have an extensive VN SQP CPD training programme planned for 2010.
"With the consensus of expert opinion on the future of worming firmly behind the use of targeted programmes incorporating worm egg counts, there has never been a more important time to get closer to clients and help them with their worming strategies."
If you would like further information, please contact your local territory manager or call the Merial Customer Support Centre on 0845 601 4236.
A leather and brass dog collar once owned by Charles Dickens is one of a number of items coming under the hammer at a sale of 'dog art' at Bonhams New York on 16th February.
You'll have to have deep pockets, though: with a nameplate inscribed 'C. Dickens, Esqe,, Gad's Hill, Place, Higham.' the collar carries an estimate of $4,000 - $6,000.
If you're feeling really flush, you could also pick up a painting by the foremost dog artist John Emms. Amongst the six Emms lots to be offered, a painting titled The Bitchpack of the Meath Foxhounds is expected to fetch $500,000 to $700,000.
The illustrated auction catalogue for the sale is online and available to view at: http://www.bonhams.com/dogs
The British Veterinary Association has launched a guidance poster to encourage farm animal vets to use anthelmintics responsibly, following ongoing concern about the development of resistance to these medicines.
According to BVA, misuse of anthelmintics in grazing animals, leading to resistance, is an increasing problem, which has now become a serious threat to the health and welfare of animals.
In response to growing concerns the BVA's Medicines Group has produced a poster that will be distributed to BVA members inside the Veterinary Record (23 January 2010 issue) and will be available to download from the BVA website.
The poster, accompanied by additional online guidance, clearly outlines Do's and Don'ts in the use of anthelmintics and carries the strong message "Think Twice Before Prescribing Anthelmintics". The poster is intended for display in veterinary practices as a reminder to vets and their clients of the need for responsible use of these medicinal products.
The poster carries advice on encouraging farm health planning and worming strategies, targeting the drug used to the parasite, the importance of not underdosing, quarantining incoming animals, and investigating and reporting suspected cases of resistance to the Veterinary Medicines Directorate (VMD). It clearly tells vets not to treat unnecessarily and not to blanket treat.
Peter Jones, Chair of the BVA's Medicines Group, said: "Every use of anthelmintics increases the risk of resistance developing. Veterinary surgeons have a duty to ensure anthelmintic use is judicious and limited to circumstances when treatment can be effective, targeted and based on sound veterinary diagnosis.
"The BVA advises all vets to work with their farming clients to develop a farm health plan that encompasses an effective worming strategy and a full grazing management programme to reduce the need for treatment.
"Vets must also promote good worming practice to ensure dosage is based on accurate weight measurements. Underdosing is a major factor in the development of resistance."
Professor Bill Reilly, President of the BVA, added: "Action to minimise the development of resistance is urgent and essential and we hope this poster will serve as a constant reminder to vets to think twice before prescribing anthelmintics."
Denmark-based consulting firm praQtice has launched a subsidiary in the UK to offer veterinary practice management consultancy services. The company says it concentrates on six business areas: strategy and business development, marketing, employee and manager development, finance, research and analysis, and training. praQtice says it has worked with a wide range of practices, from the small local practice to the large hospital, helping them bring together their mission and vision. The company also has the benefit of having an in-house marketing and communication department which it says has had considerable success - not only in Scandinavia, but in the UK when last year praQtice won a Veterinary Marketing Association award. The launch in the UK will primarily be driven by three praQtice consultants - founder and business developer Christian Kolthoff, Marketing Consultant Mario Riewerts and Business Developer Helen Kington.
Helen said: "This will be great for UK vets, largely it has been the same group of consultants working with the same thoughts and ideas for the last 10 years. We need to look beyond our borders in order to evolve. In Scandinavia you can only put a mark up of 5% on your drugs, which does not make you a profit. Thus they have learnt to be much better in delivering and pricing for their professional service, I am sure we can learn a lot from them. What we also see all over Europe is that practices are getting bigger and bigger. But as the practices grow, so does the number of problems and the partner's income rarely follows. praQtice is about quality of life and allowing yourself to dream, we then give you the tools along with helping you through the implementation to make those dreams and ambitions come true.
You can meet the team at the VPMA Congress in Oxford (28th-30th January), where founder and CEO Christian Kolthoff will be speaking. Meantime, if you would like more information about praQtice, visit www.praqtice.co.uk or telephone Helen Kington on 07765 338 607
European veterinary practitioners are to receive guidance on the appropriate use of the fluoroquinolone group of antibiotics in treating a wide range of common diseases in companion animals.
The advice has been drawn up by the REQUEST team, a multinational and multidisciplinary group of experts which met for the third time last November. Their recommendations have been designed to help ensure the continued availability of this class of antibiotics in both veterinary and human medicine.
The REQUEST initiative aims to achieve a consensus on when and how to prescribe fluoroquinolones, based on a detailed assessment of published scientific data by its panel of nine acknowledged international experts. Following earlier meetings in Lyon and Vienna they have reached a stage in this ongoing project in which they can offer specific guidance on the use of fluoroquinolones in treating three important conditions in dogs: pyoderma, bacterial diseases of the upper respiratory tract and lower urinary tract infections. They will also be offering guidance on the appropriate use of this class of antibiotics in cats to avoid the development of retinal toxicities, which may occasionally result from treatment with one particular fluoroquinolone drug, enrofloxacin.
The guidance will be presented in papers to be submitted to those scientific journals which will be easily accessible to veterinary practitioners throughout Europe. Further papers will be produced and translated into the main European languages giving guidance on fluoroquinolones use in other important bacterial conditions in dogs and cats.
In the later stages of the project, the team will be highlighting priorities for future research and will use its influence to encourage collaborative studies involving the animal health industry, practitioners, veterinary schools and other research institutions, which will validate and redefine the current recommendations. They will also advise on studies which may provide the information needed in those clinical areas where there is currently insufficient published data on which to base any practical advice, such as the use of fluoroquinolones in minor companion animal species.
The REQUEST initiative is supported by Vetoquinol, a global supplier of fluoroquinolone medicines to the veterinary community. Further support is provided by the healthcare consultancy StratAdviser Ltd, which gives assistance on methodology and other scientific matters and also guarantees the independence of the expert group.
Defra has confirmed that equine infectious anaemia (EIA) has been detected in two horses in Wiltshire following importation from Romania via Belgium.
The premises is currently under restriction and the two infected horses will be humanely destroyed in line with existing regulations. The other horses on the premises will be subject to epidemiological investigation in the coming weeks. A further two horses have also been under investigation and test results have proved negative.
The animals arrived in a group of 10 horses, nine of which originated from Romania and one from Belgium. The nine Romanian horses were tested for EIA as part of routine post-import testing. Seven horses all tested negative. The horse that originated in Belgium is due to be tested shortly.
Chief Veterinary Officer, Nigel Gibbens said: "This is the first case of equine infectious anaemia infected animals being imported into Great Britain since 1976 and shows the success of our post import testing regime. These were apparently healthy horses carrying a notifiable disease that we are keen to keep out of Great Britain. After considering the risk I have decided to take appropriate action and humanely destroy these two horses that tested positive."
Intervet/Schering-Plough Animal Health has reported that since launch, its diagnostic service RespCheck has identified infectious diseases in 15 per cent of all animals checked under the scheme.
Offered to qualifying practices for no charge and implemented by the Animal Health Trust (AHT), Intervet/Schering Plough set up RespCheck to help identify the cause of infectious respiratory problems in horses.
The RespCheck kit, which has been used to swab more than 700 horses since launch, consists of naso pharyngeal swabs, enabling two horses per yard or outbreak to be swabbed for a variety of diseases. These include equine influenza, equine herpesvirus, Streptococcus equi (strangles), pasteurella, rhinovirus and Streptococcus zooepidemicus. The swabs are sent to the AHT for analysis and the results returned direct to the vet.
John Dickerson from Chine House Equine Hospital in Leicestershire said: "The service is fantastic, made all the better by being completely free of charge! The benefits are two-fold. From the clinical perspective it means we can discount or treat potential infections in a more timely fashion; for instance, we use RespCheck to screen for any suspected infectious respiratory disease cases which enables us to deal with the problem, through quarantine and strict hygiene measures, helping to prevent the spread of the disease.
The other benefit is to our practice reputation and the standard of service we can offer. It's great to be able to provide owners with peace of mind without it costing more than our call out fee. By the time an owner calls the vet they are usually stressed and worried about their horses symptoms and need some reassurance, which is exactly what RespCheck gives them. We are confident that providing a diagnostic service that is completely free and that puts an owners mind at rest regarding the risk of an infection can only be a good thing for our practice reputation and customer care.
Last year, the service proved its worth when the screening of a recently imported horse showed the animal had equine influenza. I believe that had RespCheck not been employed, we would have had an outbreak in that particular yard."
Practices interested in knowing more about RespCheck should contact their local Intervet/Schering-Plough Veterinary Business Manager or phone the company's Veterinary Support Group on 01908 685685.
Ridgeway Research Ltd has a surplus supply of short-dated Target IgG kits on special offer.
The kits are to test for passive transfer to foals via colostrum. Each kit contains 20 tests and normally costs £74. They have been reduced to £20 to clear. The use by date is end February 2010.
If you are interested, please email jo@ridgewayresearch.co.uk, or ring 01594 530809 for further information.
The deadline for candidate nominations for the RCVS and VN Council elections is fast approaching - so please hurry if you plan to stand.
There are six seats on the RCVS Council, and two on the VN Council, due to be filled in the 2010 election, but candidate nominations must be received by 31 January 2010.
Jane Hern, RCVS Registrar said: "Getting regulation right is something that all Members and Listed/Registered VNs have power to influence. We know from the reaction we get when we propose changes or ask for your comments that vets and VNs are not backwards about coming forwards - and, like us or loathe us, what the RCVS does impacts directly on the lives of veterinary surgeons and nurses, their clients and patients."
The elections will be held in March, and decided by all veterinary surgeons and veterinary nurses who use their vote. The results will be announced early in May, with those elected taking their seats at RCVS Day in July and serving four-year terms.
All prospective candidates need to provide the signatures and registered/listed addresses of two proposers, and should also submit a short biography, 'manifesto' and photograph for inclusion in the elections booklets. Nobody can nominate more than one candidate, and no current member of the RCVS Council or VN Council may nominate anyone.
Newly elected RCVS Council members should expect to sit on at least one committee which, together with Council attendances, means a time commitment of at least six to eight days a year. Those elected to the VN Council should expect to spend approximately six to eight days attending Council meetings, working parties and subcommittees. Both RCVS Council and VN Council members' expenditures on hotels and travel are reimbursed. Their employers can also claim a standard day-rate for loss of earnings.
Nomination forms and full details relating to RCVS Council nominations can be downloaded from www.rcvs.org.uk or obtained by contacting the Executive Office (020 7222 0761 or executiveoffice@rcvs.org.uk). Nomination forms and details relating to the VN Council can be requested from Annette Amato (020 7202 0788 or a.amato@rcvs.org.uk). All nominations must be made in writing on the prescribed form and received by the Registrar on or before the closing date of 31 January 2010.
A research project funded by equine charity The Horse Trust has succeeded in killing equine sarcoid cells in vitro by silencing a gene in the virus that causes sarcoids. The researchers are now hoping to obtain funding for clinical trials using the new technique, which could result in a more effective, non-toxic treatment for sarcoids.
Sarcoids are skin tumors caused by infection with the Bovine Papillomavirus (BPV). They are the most common type of tumour found in horses - the estimated prevalence in the UK is 6-7%. Although the disease is rarely life threatening, many horses with sarcoids are euthanased because the condition is untreatable or because the horse is unsellable. Currently there is no universally effective treatment for sarcoids and if treatment fails the sarcoids will often come back worse.
However, research that was given funding by The Horse Trust offers a potential ray of hope for owners of horses affected by sarcoids. The research was published in Virus Research journal earlier this year.
The research, which was led by Professor Lubna Nasir of the University of Glasgow, found that by inhibiting the activity of a particular viral protein within sarcoid cells, the amount of viral DNA in the cells reduced. This led to a reduction in the growth of the sarcoid cells and caused the cell to die by Programmed cell-death (PCD). The researchers believe that PCD occurs because the sarcoid cells become reliant on the virus.
Professor Nasir said: "This could potentially be a major breakthrough in the treatment of sarcoids. We are now seeking funding to use this technique in clinical trials on horses that have sarcoids."
The research team inhibited the activity of a viral protein called E2, which is needed by BPV to replicate. They used a novel approach termed 'gene silencing' to suppress the activity of the gene that codes the E2 protein. The research was carried out in vitro on fibroblast cells, which had been cultured from sarcoid tissue removed from animals during surgery.
As this research was carried out in vitro, the researchers will now need to see if they can replicate the results in vivo, by developing a way of targeting the sarcoid cells in horses.
"One of the challenges with gene silencing is administering it within clinical setting - as you need to get molecules into every cell. As sarcoids are on the surface of a horse, we think administration should be relatively easy - potentially by injecting or applying a cream to the sarcoid," said Professor Nasir. "If we are able to successfully develop this technique it would be a non-toxic and easy to administer treatment for horses affected by this distressing condition."
Nasir's research could also have an impact on the treatment of lesions in cattle, which are also caused by BPV. Around 50% of cattle in the UK are estimated to have lesions. It may also help with the treatment of Human Papillomavirus (HPV) infections in humans. HPV, which is similar to BPV, can lead to various cancers in humans including cervical and vaginal cancer.
Paul Jepson, Chief Executive and Veterinary Director of The Horse Trust said: "We are really excited that the research we have funded could lead to a major breakthrough in the treatment of sarcoids."
The Kennel Club has broadly welcomed Professor Sir Patrick Bateson's 'Independent Inquiry into Dog Breeding', which has recommended that steps be taken to tackle irresponsible breeders and to change the way the public think about buying dogs.
The Kennel Club, which commissioned and funded the report in conjunction with Dogs Trust, welcomes the report's focus on irresponsible breeders who farm puppies with little concern for their welfare and those who sell poorly socialised puppies on to owners to use as 'status dogs' or as fighting weapons.
The Kennel Club agrees that additional training and support needs to be given to local authorities, which are responsible for issuing breeding licences to those people who breed five or more litters of puppies in a single year, as the current provisions are deemed to be ineffective. It agrees that compulsory microchipping of dogs and increased public education to stop people falling prey to puppy farmers and to help them find responsible breeders are necessary.
It is also glad that the report recognises the need for a 'robustly policed and well respected quality assurance scheme', consisting of breeders that buyers can trust to look after their puppies' health and welfare, and that it suggests that the Kennel Club's Accredited Breeder Scheme, with some modification could be used.
However, the Kennel Club is concerned that the report could have gone further and that its recommendations do not appear directly to cover those breeders who breed less than five litters per year and who are not part of the Kennel Club Accredited Breeder Scheme. The Kennel Club would have liked to have seen a recommendation for regulation to ensure that these breeders follow higher standards, such as compulsory health testing.
Caroline Kisko, Kennel Club spokesperson, said: "Whilst the report recognises that the majority of breeders are responsible, there are those whose actions are bringing the rest of the dog breeding community into disrepute and this needs to be stopped.
"We are glad that the report recognises that the Kennel Club has made a good start in its efforts to unite responsible breeders within its Accredited Breeder Scheme, for the benefit of puppies and puppy buyers, and we believe that this should be the basis for moving forward. We are currently working towards UKAS accreditation of the scheme as suggested by Professor Bateson.
"We agree that responsible breeders should be rewarded and believe that the show ring is the best forum for this. The report recognises that 'dog showing and judging are a powerful lever for change' and the Kennel Club is dedicated to ensuring that only the healthiest dogs are rewarded at shows.
"Public education is vital and all dog welfare organisations must continue to work together to ensure that people know what to look for when buying a dog."
The report looks at genetic diversity in breeds and recognises that the Kennel Club has banned close matings. It advises that future decisions about matings that could affect genetic diversity should be 'breed specific' and made upon evidence based scientific information and advice. To this end it is recommended that the veterinary profession should gather data to show the prevalence of certain diseases and that an advisory council should develop evidence based breeding strategies.
Mrs Kisko continued: "The Kennel Club has long recognised that genetic diversity plays a crucial role in safeguarding the health of dogs and the report is absolutely right to suggest that there are no further blanket rules in place but that decisions are based upon scientific knowledge and are made on a breed by breed basis. This is why we are well on the way to creating a new database which will revolutionise the way that we record dog health data. The data will enable us to bring out our Mate Select programme, which will help breeders to find suitable mating pairs which are most likely to produce healthy offspring. The database will go further than the report's recommendation, as the data will be attributable to specific dogs, rather than being anonymous, and will give us a better picture of the health of pedigrees and crossbreeds. Such knowledge is critical and will enable us to provide information to breeders, vets, geneticists and ultimately the puppy buyer.
"We are keen to harness as much knowledge as possible for the benefit of dogs so we welcome the principle of an advisory council whose members will work with the Kennel Club to advise on decisions about breeding and health. A structure already exists in the form of the Kennel Club's Dog Health Group with its recently extended remit. Additional independent experts include canine and human geneticists, veterinary surgeons and an epidemiologist. Using this framework for establishing the advisory council under an independent chairman would save significant sums of money, which can instead be devoted entirely to the dog health research that the report identified as being in 'urgent' need of more funding."
The Kennel Club and Dogs Trust will now arrange a meeting between all relevant parties in order to move forward with the recommendations from all three reports.
The full report may be downloaded at www.dogbreedinginquiry.com
Janssen Animal Health has announced that it has acquired the distribution rights for a range of sedatives and anaesthetics for small and large animals, including Dexdomitor, Domitor and Antisedan.
Janssen aquired the marketing and distribution rights, which were previously held by Pfizer Inc, from Orion Corporation.
Dr. Enno Gottschalk , Janssen's European Director Marketing and Sales said: "This acquisition of distribution rights results in the perfect combination of proven and effective products with the outstanding service and technical selling capabilities of Janssen Animal Health. The products include the sedative Dexdomitor and Domitor, as well as the antagonist Antisedan. Among large animals, predominantly horses, the sedative injection Domosedan is now on offer as part of the Janssen Animal Health portfolio."
A Dogs Trust Glasgow resident who made the news last January for being so obese he could not even walk has lost almost half his body weight.
Patch, a six year old Beagle Cross, weighed the same as an average six year old child - 4.5 stones (28.45kg) - when he was brought to the Rehoming Centre last year.
Staff desperately hoped 2009 would see him find a new home and see him shed almost half his bodyweight to reach his goal of 2.4 stone (15kg). After finding a new home with the MacLean family in Motherwell, exactly one year after hitting the headlines Patch is within sniffing distance of his target by weighing in at 2.9 stone (18kg).
Vets had warned that a rapid weight loss would put strain on Patch's organs and could actually harm him, so it has been a slow, careful process. He follows a strict diet and his exercise levels have been built up gradually, with careful monitoring by veterinary staff.
Claire Kelman, Dogs Trust Glasgow Assistant Centre Manager, said: "When Patch first came to us he was so obese he couldn't even walk and needed a sling to be moved from one place to another. Now he's lost the weight he can run around and properly enjoy his walks like any other dog.
It just goes to show a good diet and careful exercise can make a real impact, so maybe he can be a shining example for everyone feeling a bit bloated after the Christmas break!"
Images courtesy Centre Press Agency
The University of Glasgow Small Animal Hospital has completed a £15 million pound development, including the installation of state-of-the-art diagnostic imaging equipment from Siemens Healthcare.
A Magnetom Essenza MRI, a Somatom Spirit CT and Multix Top analogue X-ray are now in place to assist the examination of animals and to diagnose conditions quickly and accurately. A further order for an Oncor Impression linear accelerator has been placed to enable the hospital to provide cost effective and flexible radiotherapy for its animal patients.
The Essenza 1.5T MRI scanner replaces a visiting mobile MRI to provide onsite imaging. According to Siemens, the Essenza is able to give a high level of diagnostic information in just one examination. With rapid and high quality imaging, animal patients spend less time under anaesthetic and the time taken to begin treatment can be reduced.
The installation of the Somatom Spirit CT scanner allows the hospital to look beyond bone structure and into soft tissue and organ imaging. Siemens says the speed and versatility of the Spirit are ideal for veterinary CT. Alongside the Spirit, the hospital has also installed a Multix Top analogue X-ray system providing the hospital with a simple and efficient imaging tool.
Calum Paterson, Hospital Manager at Glasgow Small Animal Hospital said: "By advancing our scanning facilities we are able to increase the services we offer and provide rapid, high-resolution images for our patients. The Siemens scanners are highly suitable in terms of their size and design to be able to accommodate all the small animal patients we see."
James Weir, Regional Sales Manager at Siemens Healthcare said: "Siemens technology is designed to speed up diagnosis by providing faster examination times and high quality imaging. These key functions provide excellent quality of care to any patient, be it human or animal. The installations are transforming veterinary care by providing enhanced diagnosis and improving treatment pathways for domestic pets."
Genitrix is offering a free poster-sized treatment and dispensing guide for small animals. Designed to be pinned on the consulting room or dispensary wall, the poster sets out key data, including active ingredients, species information and application advice for the company's range of anti-parasite treatments for rabbits, ferrets, rodents, reptiles, birds and other exotic pets.
These include the ivermectin-based Xeno topical spot-on and spray range; Xenex Ultra, the permethrin-based topical spot-on preventive treatment for flystrike; Lapizole, a fenbendazole-based oral treatment for E.cuniculi and Mycozole, a miconazole-based spray for fungal infections, including ringworm.
Rob Watkins, Marketing Director at Genitrix, said: "The treatment guide provides easy to use and clear information on all our small animal products and their use for the practice team."
To request a free poster, please contact Genitrix on 01403 786345 or by email to mail@genitrix.co.uk
Dorwest Herbs has highlighted research that suggests a highly rational mode of action for kelp seaweed as an aid in the treatment of obesity when used alongside a weight reduction diet. The company is asking vets and nurses to look at the evidence and consider using licensed herbal medicines to help cats and dogs lose weight naturally. To help you evaluate the product, Dorwest is giving away 50 trial packs of Kelp Seaweed Tablets.
Mary Boughton MBE, Quality Director at Dorwest Herbs and the UK's leading specialist in the formulation of veterinary herbal medicines said: "We have lots of evidence that Kelp Seaweed Tablets work as an aid in the treatment of obesity but traditional explanations were based on the effect of iodine supplementation on thyroid function as a mode of action. That just didn't hold water for us. However, in common with many conventional medicines, the mechanisms for mode of action of herbal medicines are often not known. So, it was with some excitement that we heard of research that demonstrated that fucoxanthin, a pigment found in kelp, upregulates expression of UCP1 (uncoupling protein) and produces weight loss in the same region as conventional anti-obesity drugs."
Various studies estimate pet obesity may affect 30 to 60 per cent of pets in the UK and arthritis, heart disease and diabetes are just some of the diseases that occur with increasing frequency in obese pets. The research indicates that fucoxanthin has an effect on glucose metabolism and may lower the risk of coronary heart disease in humans. Phlorotannins found in brown seaweed have also recently been indentified as interfering with both the onset and consequences of osteoarthritis. Mary Boughton points out that multiple effects are often seen when herbal treatments are used, "Herbal treatments contain thousands of plant derived chemical compounds and are known for their diverse action, as opposed to the 'magic bullet' effect seen with conventional medicines. In a condition such as obesity where we see many disruptions of normal metabolism and several co-morbid conditions, choosing a herbal treatment makes sense. Kelp Seaweed Tablets are the logical alternative."
Dorwest has prepared a fully referenced technical information sheet detailing recent scientific studies and data from herbal formularies with reference to the role of kelp seaweed in obesity management.
To help vets and nurses further evaluate Kelp Seaweed Tablets - a licensed herbal medicine - used as part of a weight management programme the company is giving away 50 FREE trial packs containing seven weeks of Kelp Seaweed Tablets for a large breed dog, a case report sheet and the technical information sheet. There is also a prize of £100 of John Lewis shopping vouchers for the most informative case report received before the end of February 2010. There is one pack available per practice, while stocks last.
To request a technical information sheet or pack call Dorwest Herbs on 01308 897272.
All veterinary surgeons, veterinary nurses and VN students are to be invited to take part in an RCVS survey of their profession and, for the first time, these surveys will measure mental wellbeing at a population level.RCVS Registrar, Jane Hern said: "Both surveys are being undertaken on our behalf by the Institute of Employment Studies - an independent research organisation. As in previous surveys, all the data will be anonymised by the IES before being shared with us. This will ensure individuals cannot be identified."The information will provide a snapshot of the veterinary profession and help the RCVS to understand and analyse changing trends. Some of the anonymised data will also be shared with researchers at Defra and at the School of Medicine, University of Southampton, who will analyse selected topics in more depth.Jane added: "These surveys produce very useful information about the veterinary and veterinary nursing profession, not least because they usually get a good response rate.
"We will use the information, for example, in our discussions about new veterinary legislation, 24/7 and the Professional Development Phase for newly-qualified vets. So please make sure that you send the form to the IES - or fill it in online - before 8 February."The RCVS normally surveys veterinary surgeons every four years, and last surveyed veterinary nurses in 2008. To obtain concurrent data regarding vets and VNs, both these surveys are taking place at the same time. Forms can by sent back in the freepost envelope provided, or completed online at www.employmentresearch.co.uk/vs2010.htm (vets) and www.employmentresearch.co.uk/vn2010.htm (VNs). The findings of previous studies can be found at www.rcvs.org.uk/surveys.