Speaking at a press briefing at BSAVA Congress 2017, Dr Cathryn Mellersh, Head of Canine Genetics at the Animal Health Trust and a member of the WSAVA Hereditary Disease Committee, also urged vets not to shy away from telling owners if they have made a bad choice to try to deter them from making the same mistake again.
During her briefing Dr Mellersh explained that concern about hereditary disease, particularly in dogs, had grown significantly in recent years, thanks to an increased awareness of the risks it poses to animals.
Dr Mellersh also explained that this heightened awareness had coincided with a period of rapid progress in the development of tools and resources to tackle hereditary disease, including the online DNA database, created by the WSAVA’s Hereditary Disease Committee and supported by Mars Veterinary, which is accessible, free of charge to veterinary surgeons around the world.
She said: "We ask vets to advise breeders to use DNA test results to avoid breeding clinically affected dogs and to reduce the frequency of mutation within a breed, over time, without damaging genetic diversity. When selecting a test, it is important that they ensure that the test they are using is based on sound science and on the right mutation for the breed being tested."
Dr Mellersh also warned veterinary surgeons not to advise against breeding with carriers and said that dogs should not be excluded from breeding on the basis of a single mutation that they could test for. She said: "The disease mutation that the DNA test is for is not the only mutation that a carrier has. Most dogs carry at least 50 recessive mutations so, if carriers are not bred from and only clear dogs used then there is a risk that other mutations carried by these clear dogs will increase in frequency within the breed and new inherited diseases could emerge."
"The ranges of resources available to help vets in this area is growing all the time and includes the WSAVA database hosted by PennGen and a Kennel Club database which lists the DNA tests recommended or required by Assured Breeders.
"For those looking to increase their knowledge in this area, hereditary disease is one of the key issues to be discussed during this year’s WSAVA World Congress in Copenhagen from 25-28 September. Many of the world’s experts will be there and a full lecture stream is planned."
"I ask vets to work with us and to contribute to the very real progress that is being made to tackle hereditary disease, particularly in dogs. Advances in technology are driving this progress and it is also being supported by many breeders and by the Kennel Club.
"The greatest challenge we face is that of educating the general public that they should be mindful of hereditary disease when choosing a puppy and should seek out those whose breeders have had the appropriate DNA tests and clinical screens.
"It is, of course, not always possible to reach owners before they buy a puppy but should their dog later go on to develop a condition that is well-known in the breed, then I ask them to explain this to owners so that, should they buy another dog, they do not make the same mistake. As a vet, you will also often be the first port of call for advice by first time breeders and this gives you a golden opportunity to advise them as to the tests they should undertake and, depending on the results, whether they should go ahead with breeding or not.
"Working together as a profession, being willing to discuss difficult issues with owners and breeders and utilising the resources and tools created by organisations such as the WSAVA, are all required to ensure that we increase the momentum we are already achieving in tackling canine hereditary disease in the UK and around the world."
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