Zoetis has announced the European launch of Suvaxyn Circo, a new monovalent killed virus vaccine which the company says reduces viral load in blood and in lymphoid tissues as well as faecal shedding caused by infection with PCV2.

The vaccine has been developed from Suvaxyn Circo+MH RTU, and also contains MetaStim as adjuvant 1.

MetaStim is an emulsion containing a metabolisable (non-mineral) oil and is used in vaccines to help elicit both humoral and a cell-mediated immune responses. Zoetis says it is thought to preserve the vaccine components so the antigens are released slowly as compared to other types of adjuvants2. 

Alvaro Aldaz, Director Commercial Development and Innovation, Swine, Zoetis, said: "The safety and efficacy of MetaStim has been well documented given its use in several swine, cattle and equine vaccines for the past several years. 

"In fact, the MetaStim adjuvant is currently used in our bivalent vaccine – Suvaxyn Circo+MH RTU. Suvaxyn Circo is the monovalent PCV2 fraction of the parent vaccine and it delivers a similar performance profile for PCV2 protection."

More than 250 million pigs are vaccinated against Circovirus every year in Europe.

Professor Hans Nauwynck, Director of the Laboratory of Virology at Ghent University said: "Vaccination of piglets against Circovirus has become a standard in pig farms across Europe.

"The goal is achieving strong immunity, both cell mediated and antibodies, against a virus that is always in the farm.

"Veterinarians should consider several factors when deciding the best timing for vaccination, being especially important the levels of maternal immunity in the pigs to be vaccinated, the presence of co-infections like PRRSV and the expected infection pattern in the farm."  

Suvaxyn Circo is a new tool for veterinarians and producers who prefer monovalent vaccines. In situations where early vaccination of piglets against M.hyo is preferred, for example using Suvaxyn MH-One which is licensed for administration from one week of age, there will be a need to give a separate monovalent vaccine to cover PCV2. In such cases, Suvaxyn Circo from three weeks of age can be considered as an option. 

Suvaxyn Circo is available in 50- and 125-dose vials.

For more information, contact your Zoetis representative.

References

  1. D.W. Horohov, J. Dunham, C.Liu, A.Betancourt, J.C Stewart, Veterinary Immunology and Immunopathology 164 (2015) 24-29
  2. J. Jeong, C. Park, K. Choi, C. Chae, Veterinary Microbiology 182 (2016) 178-186

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