Boehringer Ingelheim has announced the results of an independent three-year study which demonstrates that dogs suffering from the most common type of heart failure lived longer (average time in the study of 267 days vs. 140 days) when treated with the product Vetmedin (pimobendan) compared with the ACE inhibitor benazepril hydrochloride.
According to Boehringer, results from the QUEST (Quality of Life and Extension of Survival Time) study, published in the September/October 2008 issue of the Journal of Veterinary Internal Medicine, mark a significant milestone in canine cardiac health.
25% of all small to medium-sized dogs over the age of seven are likely to suffer from heart disease at some point in their life, and 75% of those cases are caused by myxomatous mitral valve disease (MMVD), sometimes known as "valvular insufficiency" or "endocardiosis".
Adrian Boswood from the Royal Veterinary College, London, a Veterinary Cardiology Specialist and a lead-investigator on the study, said: "With QUEST demonstrating that dogs treated with Vetmedin live on average nearly twice as long as those on benazepril, it is now time for us as veterinary cardiologists and practising veterinarians to look again at how we are treating our patients suffering from this serious condition."
Dr. Michael O'Grady from the Ontario Veterinary College, University of Guelph, a fellow lead-investigator added, "The QUEST study provides compelling evidence that dogs with the most common form of heart failure should be receiving Vetmedin® as an essential part of their treatment regimen."
QUEST is the largest international study ever conducted looking at treatment for congestive heart failure (CHF) caused by MMVD, with 260 dogs studied in 11 countries, across three continents, over a period of three years.
The study was conducted by a team of 32 independent veterinary cardiologists from Australia, Canada, France, Germany and the United Kingdom among other countries.
For more information on the QUEST study and on CHF caused by MMVD, see http://www.questtrial.com/
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