The Kennel Club has launched the Genetics Centre at the Animal Health Trust (AHT) to accelerate research into inherited canine disease.

It aims to create further diagnostic tests which, together with breeding advice, will improve the health and welfare of generations of dogs.

Because of the small gene pool in purebred dogs, inherited diseases resulting from single gene mutations are more likely to occur than in their cross bred cousins. This can lead to significant welfare issues. There are more than five million purebred dogs in the UK alone and many of these will benefit from the findings of the Genetics Centre.

Over the next five years, the centre aims to investigate 25 inherited diseases. It will develop, where possible, screening tests to determine affected and carrier dogs that can be performed with simple mouth swabs. In deciding which diseases to investigate, the joint Kennel Club and AHT team will look at their impact on the health and welfare of dogs, but also on the support of breeders and access to data and samples.

Dr Peter Webbon, Chief Executive of the AHT, said: "We're delighted to work in partnership with the Kennel Club on this important welfare issue. Our level of skill and expertise within this field is unparalleled and the new centre enables us to extend our current range of DNA tests.

"We hope, in time, this will equip breeders with essential information so they can plan successful breeding strategies to avoid the birth of affected dogs, and ultimately, to eliminate disease from breeds at risk."

Dr. Cathryn Mellersh and Dr. Sarah Blott, two of the AHT's genetics experts, will lead the Centre. Both have been fundamental in identifying defective genes and developing screening tests which identify a dog's genetic status and minimise the risk of producing affected puppies.

The Centre will also introduce new approaches in dog breeding.  One major advance will be estimated breeding values (EBVs). These will enable whole dog populations to be evaluated for inherited disease - even if individuals haven't been scanned or DNA tested themselves.

Caroline Kisko, Kennel Club spokesperson, said: "The Kennel Club is pleased to support research which improves the health and happiness of dogs. Working in partnership with the Animal Health Trust means we can start to tackle the problem of inherited disease much quicker.  

"We have already made significant investment in this area, and are now delighted to step up the scope of this research. It is a very real possibility that through this Centre we will be able to eradicate certain inherited diseases in some dogs."

Dr Ed Hall, President of BSAVA, said: "Inherited disease is one part of a complex issue involved with breeding pedigree dogs.

"I personally welcome any efforts to improve our current understanding of the area and trust that the Kennel Club Genetics Centre will make massive progress in the next five years in order to enable owners to make informed breeding decisions and, in time, to reduce the effect of inherited disease."

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