Exocrine Pancreatic insufficiency (EPI) Treatment Study 

Aran Mas, P-J.M.Noble , A.J.German

EPI is a common condition in dogs with early response to therapy being critical for positive outcomes (Batchelor et al, 2007). Pancreatic enzyme supplementation is the key component of therapy in EPI. Numerous enzyme preparations exist for use in dogs, some of which are enteric-coated and some uncoated.  Although one retrospective study on treatment of EPI suggested a better response with uncoated preparations (Hall et al., 1991), there was no difference in response amongst preparations in a more recent study (Batchelor et al., 2007).  However, prospective clinical trials, on treatment of EPI, are lacking.

The Small Animal Teaching Hospital, University of Liverpool, is performing the first randomised double-blind trial to examine the effect of enteric coating on efficacy of pancreatic enzyme supplementation in the treatment of canine EPI. We are aiming to recruit dogs recently diagnosed with EPI for inclusion in this trial. Enrolled patients will undergo clinical evaluation, two months of treatment and follow-up advice, all free of charge.

Inclusion/exclusion  criteria and contact detail can be found in the SAMSOC Wiki

Other Projects listed in the SAMSOC WIKI

Angie Hibbert at the Feline Centre (Bristol)- Congenital PSS in Birman Cats - DNA Project

Harriet Syme and Colleagues RVC - are recruiting cases for a clinical trail evaluating  the use of oral phosphate binders in Feline Chronic Kidney Disease

Stijn Nelson’s- Diabetes Treatment Survey for vets, nurses and owners

Brain Catchpole and Lucy Davidson - are collaborating with a number of centres to investigate the genetic basis of several canine endocrine disorders. They are keen to recruit samples (serum and EDTA blood) from dogs suffering from a number of endocrine disorders 

NOTE- If you would like to announce recruitment details for a clinical trial, please logo onto to the SAMSoc Wiki or contact a member of the SAMSOC committee.

PS: Whilst you're here, take a moment to see our latest job opportunities for vets.