This was an aspirate from a foreign body reaction in a dog. Notice the marked variability in the macrophage morphology. Some macrophages are spindle shaped and some epithelioid and display phagocytosis. A ruptured squamous cyst was suspected.
A: Spindleoid clumped macrophages with a central plasma cell and peripheral neutrophils.
B: Refractile foreign material (presumed keratin).
C: Epithelioid macrophages displaying neutrophil phagocytosis.
D: Foreign body giant cell.
First published: Wed, Dec 1 2010